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KMID : 1134820090380050555
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Journal of the Korean Society of Food Science and Nutrition
2009 Volume.38 No. 5 p.555 ~ p.560
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ABTS Radical Scavenging and Anti-Tumor Effects of Tricholoma matsutake Sing. (Pine Mushroom)
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Kim Young-Eon
Yang Ji-Won
Lee Chang-Ho
Kwon Eun-Kyung
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Abstract
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Pine mushroom (Tricholoma matsutake Sing.) is an expensive and highly prized delicacy in Korean and Japanese cuisines with its unique flavor and functional properties. The pine mushroom juice (PMJ) was investigated for its antioxidant and anti-tumor activities with ABTS radical scavenging method and MTT assay. The phenolic contents in pine mushroom juice ranged from 1.19 to 54.99 GAEs ㎎/100 ㎖ at the concentrations of 1~50 ㎎/㎖. The ABTS radical scavenging activities of pine mushroom juice were 7.0%, 81.7% and 91.8% at the concentrations of 1, 10 and 50 ㎎/㎖, respectively. The IC50 values of pine mushroom juice were 605.9, 788.4, 583.6 and 232.5 ㎍/㎖ on the cytotoxicities against AGS, HeLa, HepG2 and HT-29, respectively, and PMJ showed the strongest growth inhibitory activity against HT-29 cell. These results suggested therapeutic potential for pine mushroom juice as an anti-oxidant and anti-tumor agent.
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KEYWORD
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Tricholoma matsutake, antioxidant effect, anti-tumor effect
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